Overview
- Form
- capsule
- Category
- Supplement
Moderate,Mood support,joint health,liver function
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SAMe
Moderate EvidenceLoading goal mappings...
Supported Health Goals
Mood Support
Moderate EvidenceSupport balanced mood and emotional wellbeing
Mood support, joint health
Scientific Studies (4)
Study protocol for a multicenter randomised controlled trial on the (cost)effectiveness of biopsy combined with same-session MR-guided LITT versus biopsy alone in patients with primary irresectable glioblastoma (EMITT trial).
PrimaryBMC cancer· 2023· meta analysis
As effective as conventional antidepressants for mild-to-moderate depression
View Study →S-Adenosylmethionine (SAMe) monotherapy for depression: an 8-week double-blind, randomised, controlled trial.
PrimaryPsychopharmacology· 2020· rct
Effective monotherapy for depression
View Study →SAMe (S-adenosylmethionine).
PrimaryHarvard review of psychiatry· 2000· n=67· rct
Significant improvement in depression scores comparable to tricyclic antidepressants
View Study →S-Adenosylmethionine for osteoarthritis of the knee or hip.
The Cochrane database of systematic reviews· 2009· systematic review
Evidence for osteoarthritis of knee or hip
View Study →Safety & Interactions
⚠️ Severe Interactions Detected
Please consult a healthcare provider before using this supplement with other medications or supplements.
severe Interaction
May cause serotonin syndrome
Recommendation: Avoid combination, seek medical guidance
life threatening Interaction
May cause serotonin syndrome
Recommendation: DO NOT COMBINE
life threatening Interaction
Combination may increase risk of serotonin syndrome
Recommendation: Avoid combination. Use one at a time.
moderate Interaction
Both affect hormone and neurotransmitter balance
Recommendation: Medical supervision recommended
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