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Vitamin D3

Strong Evidence
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Overview

Form
capsule
Category
Vitamin

Budget,Strong evidence for bone health,immunity; deficiency linked to depression

Supported Health Goals

Energy & Fatigue

Strong Evidence

Boost energy levels and reduce fatigue

Deficiency linked to fatigue and depression

Immune Support

Strong Evidence

Strengthen immune system function

Immune system support

Inflammation & Pain Relief

Moderate Evidence

Reduce systemic inflammation and manage pain

Anti-inflammatory in certain conditions

Joint Health

Moderate Evidence

Support joint comfort and mobility

Joint comfort in certain conditions

Mood Support

Moderate Evidence

Support balanced mood and emotional wellbeing

Deficiency linked to mood disorders

Scientific Studies (3)

The effect of vitamin D supplementation on primary depression: A meta-analysis.

Primary
J Affect Disord· 2024· meta analysis

Reduced depression scores, especially in clinically depressed patients

View Study →

Vitamin D protects against depression: Evidence from an umbrella meta-analysis on interventional and observational meta-analyses.

Primary
Pharmacol Res· 2023· meta analysis

Vitamin D supplementation has protective effects against depression

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Vitamin D deficiency and depression in adults: systematic review and meta-analysis.

Primary
Br J Psychiatry· 2013· meta analysis

Significant association between vitamin D deficiency and depression

View Study →

Safety & Interactions

moderate Interaction

Enhanced immune support when combined

Recommendation: Good combination for immune support

moderate Interaction

Vitamin K2 directs calcium to bones, while D3 aids absorption

Recommendation: Recommended stack for bone and cardiovascular health

mild Interaction

May reduce iron absorption slightly

Recommendation: Consider separate dosing

moderate Interaction

Enhanced energy and mood support

Recommendation: Good combination for energy and mood

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