Overview
- Form
- capsule
- Category
- Hormone
Precursor to steroid hormones; cognitive support
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Pregnenolone
Moderate EvidenceLoading goal mappings...
Scientific Studies (3)
Pregnenolone reduces provoked craving and cocaine use in men and women with cocaine use disorder: A pilot trial.
PrimaryDrug and alcohol dependence· 2025· rct
Reduced craving and cocaine use in use disorder
View Study →Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia.
PrimaryPsychopharmacology· 2014· n=22· rct
Improved negative symptoms in schizophrenia
View Study →A randomized, double-blind, placebo-controlled trial of pregnenolone for bipolar depression.
PrimaryNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology· 2014· n=70· rct
Improved cognition and reduced fatigue in healthy older adults
View Study →Safety & Interactions
moderate Interaction
Both are hormone precursors, complex interaction
Recommendation: Medical supervision strongly recommended
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